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How to layer Adapalene

Does It Mix engine · layering

At night, on clean, dry skin, before moisturizer.

Where it goes

  1. Cleanse and pat skin fully dry.
  2. Apply a pea-sized amount of the retinoid.
  3. Moisturizer on top. Sensitive? Try moisturizer, retinoid, moisturizer.
  4. Next morning: sunscreen.

Easy partners

NiacinamideHyaluronic AcidBenzoyl PeroxideSunscreenCeramidesPeptides

Keep apart

Retinol · No, not togetherVitamin C · Yes, with timingTretinoin · No, not togetherSalicylic Acid · Yes, with timingGlycolic Acid · Yes, with timingAzelaic Acid · Yes, with care

Full AM and PM order: layering guide · build yours in the vanity.

Sources

  1. A review of adapalene in the treatment of acne vulgaris. J Adolesc Health. 2008;43(5).
  2. Martin B, et al. Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. Br J Dermatol. 1998;139 Suppl 52:8-11.

Reviewed by the Does It Mix editorial team, . Methodology.

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