Adapalene + Ceramides

Can you use Adapalene with Ceramides?

Yes

Yes. Ceramides is a good partner for Adapalene.

Why

Ceramides is gentle and can help offset the dryness and irritation retinoids cause. There is no known conflict.

How to use them together

  1. Apply Adapalene at night on clean, dry skin.
  2. Use Ceramides before or after it (thinnest texture first), or as your moisturizer step.
  3. Sunscreen every morning.

Who should be careful

Retinoids are not recommended during pregnancy without medical advice. People with very sensitive skin, rosacea or eczema should patch test new products first.

About the ingredients

Adapalene: A synthetic retinoid (Differin) for acne, available over the counter at 0.1% in the US. It is more chemically stable than tretinoin, including next to benzoyl peroxide.

Ceramides: Lipids that make up a large part of the skin barrier. Ceramide moisturizers help offset dryness from actives.

FAQ

Can I use Adapalene and Ceramides together?

Yes. Ceramides is a good partner for Adapalene.

Should I use Adapalene or Ceramides in the morning or at night?

Apply Adapalene at night on clean, dry skin. Use Ceramides before or after it (thinnest texture first), or as your moisturizer step.

Who should be careful combining Adapalene and Ceramides?

Retinoids are not recommended during pregnancy without medical advice. People with very sensitive skin, rosacea or eczema should patch test new products first.

Do I need sunscreen with Adapalene and Ceramides?

Yes. Daily broad-spectrum SPF 30+ is recommended with any active skincare routine.

Sources

Studies and reviews on these ingredients and, where available, on this specific combination.

  1. A review of adapalene in the treatment of acne vulgaris. J Adolesc Health. 2008;43(5).
  2. Martin B, et al. Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. Br J Dermatol. 1998;139 Suppl 52:8-11.
  3. Meckfessel MH, Brandt S. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. J Am Acad Dermatol. 2014;71(1):177-184.

Last reviewed: . Not medical advice.

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