Can you use Adapalene with Niacinamide?
Yes. Niacinamide is a good partner for Adapalene.
Why
Niacinamide is gentle and can help offset the dryness and irritation retinoids cause. There is no known conflict.
How to use them together
- Apply Adapalene at night on clean, dry skin.
- Use Niacinamide before or after it (thinnest texture first), or as your moisturizer step.
- Sunscreen every morning.
Who should be careful
Retinoids are not recommended during pregnancy without medical advice. People with very sensitive skin, rosacea or eczema should patch test new products first.
About the ingredients
Adapalene: A synthetic retinoid (Differin) for acne, available over the counter at 0.1% in the US. It is more chemically stable than tretinoin, including next to benzoyl peroxide.
Niacinamide: Vitamin B3. Well tolerated, supports the skin barrier and helps with redness, oil and uneven tone.
FAQ
Can I use Adapalene and Niacinamide together?
Yes. Niacinamide is a good partner for Adapalene.
Should I use Adapalene or Niacinamide in the morning or at night?
Apply Adapalene at night on clean, dry skin. Use Niacinamide before or after it (thinnest texture first), or as your moisturizer step.
Who should be careful combining Adapalene and Niacinamide?
Retinoids are not recommended during pregnancy without medical advice. People with very sensitive skin, rosacea or eczema should patch test new products first.
Do I need sunscreen with Adapalene and Niacinamide?
Yes. Daily broad-spectrum SPF 30+ is recommended with any active skincare routine.
Sources
Studies and reviews on these ingredients and, where available, on this specific combination.
- A review of adapalene in the treatment of acne vulgaris. J Adolesc Health. 2008;43(5).
- Martin B, et al. Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. Br J Dermatol. 1998;139 Suppl 52:8-11.
- Bissett DL, et al. Niacinamide: a B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31(7 Pt 2):860-865.
Related combinations
- Can you use Retinol with Niacinamide?
- Can you use Vitamin C with Niacinamide?
- Can you use Tretinoin with Niacinamide?
- Can you use Niacinamide with Salicylic Acid?
- Can you use Niacinamide with Hyaluronic Acid?
- Can you use Niacinamide with Glycolic Acid?
- Can you use Niacinamide with Benzoyl Peroxide?
- Can you use Niacinamide with Sunscreen?