What can you mix with Vitamin C?

An antioxidant (L-ascorbic acid and derivatives) used for brightening and protection against UV-related oxidative stress. Pure L-ascorbic acid serums are acidic and can sting.

• Retinol Yes, with timing
• Niacinamide Yes
• Tretinoin Yes, with timing
• Salicylic Acid Yes, with timing
• Hyaluronic Acid Yes
• Glycolic Acid Yes, with timing
• Benzoyl Peroxide Yes, with timing
• Sunscreen Yes
• Adapalene Yes, with timing
• Azelaic Acid Yes, with care
• Lactic Acid Yes, with timing
• Ceramides Yes
• Copper Peptides Yes, with timing
• Bakuchiol Yes
• AHA/BHA Peel Yes, with timing
• Vitamin E Yes
• Ferulic Acid Yes

Sources

1. Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866.
2. Al-Niaimi F, Chiam NYZ. Topical vitamin C and the skin: mechanisms of action and clinical applications. J Clin Aesthet Dermatol. 2017;10(7):14-17.

Last reviewed: 2026-10-21. Not medical advice.