Can you use La Roche-Posay Retinol B3 Serum with La Roche-Posay Pure Vitamin C10 Serum?
Yes, with timing
Use them at different times of day or on different nights.
Based on 8 active-ingredient pairings, listed below.
How to use them
- AM: vitamin C serum, moisturizer, sunscreen.
- PM: Retinol, then moisturizer.
- If both feel fine after a few weeks, keep going. If not, use vitamin C fewer days.
Every active pairing checked
| Actives | Verdict | Why |
|---|---|---|
| Retinol + Vitamin C | Yes, with timing | Yes, with timing. Use vitamin C in the morning and Retinol at night. |
| Niacinamide + Vitamin C | Yes | Yes. Vitamin C and niacinamide can be used together. |
| Niacinamide + Hyaluronic Acid | Yes | Yes. Niacinamide and hyaluronic acid are one of the safest combinations in skincare. |
| Niacinamide + Peptides | Yes | Yes. Niacinamide and Peptides can be used together. |
| Hyaluronic Acid + Vitamin C | Yes | Yes. Vitamin C and hyaluronic acid are a classic morning pair. |
| Hyaluronic Acid + Peptides | Yes | Yes. Hyaluronic Acid and Peptides can be used together. |
| Retinol + Hyaluronic Acid | Yes | Yes. Hyaluronic acid is an easy, gentle partner for retinol. |
| Retinol + Peptides | Yes | Yes. Peptides is a good partner for Retinol. |
What's in each product
Key actives
La Roche-Posay Retinol B3 Serum
Actives read from the published ingredient list (as transcribed on INCIDecoder). Formulas change; check your bottle.
Key actives
La Roche-Posay Pure Vitamin C10 Serum
Actives read from the published ingredient list (as transcribed on INCIDecoder). Formulas change; check your bottle.
Sources
- Kafi R, et al. Improvement of naturally aged skin with vitamin A (retinol). Arch Dermatol. 2007;143(5):606-612.
- Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866.
- Al-Niaimi F, Chiam NYZ. Topical vitamin C and the skin: mechanisms of action and clinical applications. J Clin Aesthet Dermatol. 2017;10(7):14-17.
- Bissett DL, et al. Niacinamide: a B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31(7 Pt 2):860-865.
- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: a key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258.
- Gorouhi F, Maibach HI. Role of topical peptides in preventing or treating aged skin. Int J Cosmet Sci. 2009;31(5):327-345.
DM
Reviewed by the Does It Mix editorial team
Last reviewed . Product verdicts combine our ingredient-pair verdicts for each product's key actives. We are not affiliated with these brands. Methodology.