Vitamin C + Glycolic Acid (AHA)

Can you use Vitamin C with Glycolic Acid?

Yes, with timing

Yes, with timing. Use vitamin C in the morning and Glycolic Acid at night.

Why

L-ascorbic acid serums and glycolic acid are both low-pH products. Layered back-to-back, they are more likely to sting and over-exfoliate, especially on sensitive skin. Vitamin C fits best in the morning under sunscreen, while glycolic acid fits best in the evening a few times a week.

How to use them together

  1. AM: vitamin C, moisturizer, sunscreen.
  2. PM (a few nights a week): Glycolic Acid, moisturizer.

Who should be careful

Sensitive skin should introduce one at a time.

About the ingredients

Vitamin C: An antioxidant (L-ascorbic acid and derivatives) used for brightening and protection against UV-related oxidative stress. Pure L-ascorbic acid serums are acidic and can sting.

Glycolic Acid (AHA): The smallest alpha hydroxy acid. A chemical exfoliant for texture and dullness. It can increase sun sensitivity.

FAQ

Can I use Vitamin C and Glycolic Acid together?

Yes, with timing. Use vitamin C in the morning and Glycolic Acid at night.

Should I use Vitamin C or Glycolic Acid in the morning or at night?

AM: vitamin C, moisturizer, sunscreen. PM (a few nights a week): Glycolic Acid, moisturizer.

Who should be careful combining Vitamin C and Glycolic Acid?

Sensitive skin should introduce one at a time.

What if my skin gets irritated using Vitamin C and Glycolic Acid?

Stop the stronger active, keep a gentle cleanser, moisturizer and sunscreen, and reintroduce one product at a time once skin calms down. See a dermatologist if irritation persists.

Sources

Studies and reviews on these ingredients and, where available, on this specific combination.

  1. Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866.
  2. Al-Niaimi F, Chiam NYZ. Topical vitamin C and the skin: mechanisms of action and clinical applications. J Clin Aesthet Dermatol. 2017;10(7):14-17.
  3. Kornhauser A, Coelho SG, Hearing VJ. Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clin Cosmet Investig Dermatol. 2010;3:135-142.
  4. Kaidbey K, et al. Topical glycolic acid enhances photodamage by ultraviolet light. Photodermatol Photoimmunol Photomed. 2003;19(1):21-27.

Last reviewed: . Not medical advice.

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