Niacinamide + Ceramides

Can you use Niacinamide with Ceramides?

Yes

Yes. Niacinamide and Ceramides can be used together.

Why

There is no known conflict between Niacinamide and Ceramides. Both are generally well tolerated and are commonly found together in routines.

How to use them together

  1. Layer from thinnest to thickest texture.
  2. Finish with moisturizer, and sunscreen in the morning.

Who should be careful

People with very sensitive skin, rosacea or eczema should patch test new products first.

About the ingredients

Niacinamide: Vitamin B3. Well tolerated, supports the skin barrier and helps with redness, oil and uneven tone.

Ceramides: Lipids that make up a large part of the skin barrier. Ceramide moisturizers help offset dryness from actives.

FAQ

Can I use Niacinamide and Ceramides together?

Yes. Niacinamide and Ceramides can be used together.

Should I use Niacinamide or Ceramides in the morning or at night?

Layer from thinnest to thickest texture. Finish with moisturizer, and sunscreen in the morning.

Who should be careful combining Niacinamide and Ceramides?

People with very sensitive skin, rosacea or eczema should patch test new products first.

Do I need sunscreen with Niacinamide and Ceramides?

Yes. Daily broad-spectrum SPF 30+ is recommended with any active skincare routine.

Sources

Studies and reviews on these ingredients and, where available, on this specific combination.

  1. Efficacy of ceramides and niacinamide-containing moisturizer versus hydrophilic cream in combination with topical anti-acne treatment in mild to moderate acne vulgaris: a split-face RCT. J Cosmet Dermatol. 2024.
  2. Bissett DL, et al. Niacinamide: a B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31(7 Pt 2):860-865.
  3. Meckfessel MH, Brandt S. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. J Am Acad Dermatol. 2014;71(1):177-184.

Last reviewed: . Not medical advice.

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