How to layer Tretinoin
Does It Mix engine · layering
At night, on clean, dry skin, before moisturizer.
Where it goes
- Cleanse and pat skin fully dry.
- Apply a pea-sized amount of the retinoid.
- Moisturizer on top. Sensitive? Try moisturizer, retinoid, moisturizer.
- Next morning: sunscreen.
Easy partners
Keep apart
Retinol · No, not togetherVitamin C · Yes, with timingSalicylic Acid · Yes, with timingGlycolic Acid · Yes, with timingBenzoyl Peroxide · Yes, with timingAdapalene · No, not together
Full AM and PM order: layering guide · build yours in the vanity.
Sources
- Zaenglein AL, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016;74(5):945-973.
- Martin B, et al. Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. Br J Dermatol. 1998;139 Suppl 52:8-11.