Azelaic Acid + Vitamin E

Can you use Azelaic Acid with Vitamin E?

Yes

Yes. Azelaic Acid and Vitamin E can be used together.

Why

There is no known conflict between Azelaic Acid and Vitamin E. Both are generally well tolerated and are commonly found together in routines.

How to use them together

  1. Layer from thinnest to thickest texture.
  2. Finish with moisturizer, and sunscreen in the morning.

Who should be careful

People with very sensitive skin, rosacea or eczema should patch test new products first.

About the ingredients

Azelaic Acid: A multitasking acid for acne, rosacea and hyperpigmentation. Usually well tolerated, though it can tingle at first.

Vitamin E: A fat-soluble antioxidant (tocopherol) common in moisturizers and antioxidant serums. It can rarely cause contact allergy.

FAQ

Can I use Azelaic Acid and Vitamin E together?

Yes. Azelaic Acid and Vitamin E can be used together.

Should I use Azelaic Acid or Vitamin E in the morning or at night?

Layer from thinnest to thickest texture. Finish with moisturizer, and sunscreen in the morning.

Who should be careful combining Azelaic Acid and Vitamin E?

People with very sensitive skin, rosacea or eczema should patch test new products first.

Do I need sunscreen with Azelaic Acid and Vitamin E?

Yes. Daily broad-spectrum SPF 30+ is recommended with any active skincare routine.

Sources

Studies and reviews on these ingredients and, where available, on this specific combination.

  1. The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications. Postepy Dermatol Alergol. 2023.
  2. Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. Cochrane Database Syst Rev. 2020;5:CD011368.
  3. Keen MA, Hassan I. Vitamin E in dermatology. Indian Dermatol Online J. 2016;7(4):311-315.

Last reviewed: . Not medical advice.

Related combinations