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Can you use The Ordinary Niacinamide 10% + Zinc 1% with The Ordinary Alpha Arbutin 2% + HA?

Yes

Their key actives have no known conflict.

Based on 2 active-ingredient pairings, listed below.

How to use them

  1. Apply the thinner, more watery product first, then the thicker one.
  2. Finish with moisturizer, and sunscreen in the morning.

Every active pairing checked

ActivesVerdictWhy
Niacinamide + alpha arbutinYesYes. Niacinamide and alpha arbutin are an easy pairing for dark spots.
Niacinamide + hyaluronic acidYesYes. Niacinamide and hyaluronic acid have no known conflict.

What's in each product

Key actives

The Ordinary Niacinamide 10% + Zinc 1%

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Key actives

The Ordinary Alpha Arbutin 2% + HA

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Actives read from each brand's published ingredient list (as transcribed on INCIDecoder and INCIDecoder). Formulas change; check your bottle.

Sources

  1. Bissett DL, et al. Niacinamide: a B vitamin that improves aging facial skin appearance. Dermatol Surg. 2005;31(7 Pt 2):860-865.
  2. Tanno O, Ota Y, Kitamura N, Katsube T, Inoue S. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Br J Dermatol. 2000;143(3):524-531.
  3. Draelos ZD, Matsubara A, Smiles K. The effect of 2% niacinamide on facial sebum production. J Cosmet Laser Ther. 2006;8(2):96-101.
  4. Boo YC. Arbutin as a skin depigmenting agent with antimelanogenic and antioxidant properties. Antioxidants (Basel). 2021;10(7):1129.
  5. Austin E, Nguyen JK, Jagdeo J. Topical treatments for melasma: a systematic review of randomized controlled trials. J Drugs Dermatol. 2019;18(11):S1545961619P1156X.
  6. SCCS, Degen GH. Opinion of the Scientific Committee on Consumer Safety (SCCS): Opinion on the safety of the use of alpha-arbutin in cosmetic products. Regul Toxicol Pharmacol. 2016;74:75-6.
  7. Tantanasrigul P, Sripha A, Chongmelaxme B. The Efficacy of Topical Cosmetic Containing Alpha-Arbutin 5% and kojic acid 2% Compared With Triple Combination Cream for the Treatment of Melasma: A Split-Face, Evaluator-Blinded Randomized Pilot Study. J Cosmet Dermatol. 2025;24(1):e16562.
  8. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: a key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258.
  9. Pavicic T, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.
  10. Zanchetta C, Scandolera A, Reynaud R. Hyaluronic Acid in Topical Applications: The Various Forms and Biological Effects of a Hero Molecule in the Cosmetics Industry. Biomolecules. 2025;15(12):1656.
  11. U.S. Food and Drug Administration. Dermal Fillers (Soft Tissue Fillers). Content current as of 07/06/2023.
  12. INCIDecoder. The Ordinary Niacinamide 10% + Zinc 1%: ingredient list.
  13. INCIDecoder. The Ordinary Alpha Arbutin 2% + HA: ingredient list.
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