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Can you use The Ordinary Azelaic Acid Suspension 10% with The Ordinary Alpha Arbutin 2% + HA?

Yes

Their key actives have no known conflict.

Based on 4 active-ingredient pairings, listed below.

How to use them

  1. Apply the thinner, more watery product first, then the thicker one.
  2. Finish with moisturizer, and sunscreen in the morning.

Every active pairing checked

ActivesVerdictWhy
Azelaic Acid + alpha arbutinYesYes. Azelaic acid and alpha arbutin can be used together.
Azelaic Acid + hyaluronic acidYesYes. Azelaic acid and hyaluronic acid can be used together.
Vitamin E + alpha arbutinYesYes. Vitamin E and alpha arbutin can be used together.
Vitamin E + hyaluronic acidYesYes. Hyaluronic acid and vitamin E can be used together.

What's in each product

Key actives

The Ordinary Azelaic Acid Suspension 10%

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Key actives

The Ordinary Alpha Arbutin 2% + HA

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Actives read from each brand's published ingredient list (as transcribed on INCIDecoder and INCIDecoder). Formulas change; check your bottle.

Sources

  1. Sauer N, et al. The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications. Postepy Dermatol Alergol. 2023;40(6):716-724.
  2. Liu H, et al. Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. Cochrane Database Syst Rev. 2020;5(5):CD011368.
  3. Boo YC. Arbutin as a skin depigmenting agent with antimelanogenic and antioxidant properties. Antioxidants (Basel). 2021;10(7):1129.
  4. Austin E, Nguyen JK, Jagdeo J. Topical treatments for melasma: a systematic review of randomized controlled trials. J Drugs Dermatol. 2019;18(11):S1545961619P1156X.
  5. SCCS, Degen GH. Opinion of the Scientific Committee on Consumer Safety (SCCS): Opinion on the safety of the use of alpha-arbutin in cosmetic products. Regul Toxicol Pharmacol. 2016;74:75-6.
  6. Tantanasrigul P, Sripha A, Chongmelaxme B. The Efficacy of Topical Cosmetic Containing Alpha-Arbutin 5% and kojic acid 2% Compared With Triple Combination Cream for the Treatment of Melasma: A Split-Face, Evaluator-Blinded Randomized Pilot Study. J Cosmet Dermatol. 2025;24(1):e16562.
  7. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: a key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258.
  8. Pavicic T, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.
  9. Zanchetta C, Scandolera A, Reynaud R. Hyaluronic Acid in Topical Applications: The Various Forms and Biological Effects of a Hero Molecule in the Cosmetics Industry. Biomolecules. 2025;15(12):1656.
  10. U.S. Food and Drug Administration. Dermal Fillers (Soft Tissue Fillers). Content current as of 07/06/2023.
  11. Keen MA, Hassan I. Vitamin E in dermatology. Indian Dermatol Online J. 2016;7(4):311-315.
  12. Thiele JJ, Hsieh SN, Ekanayake-Mudiyanselage S. Vitamin E: critical review of its current use in cosmetic and clinical dermatology. Dermatol Surg. 2005;31(7 Pt 2):805-813.
  13. INCIDecoder. The Ordinary Azelaic Acid Suspension 10%: ingredient list.
  14. INCIDecoder. The Ordinary Alpha Arbutin 2% + HA: ingredient list.
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