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Can you use Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant with The Ordinary Mandelic Acid 10% + HA?

Yes, with care

They can work together, but build up slowly.

Based on 2 active-ingredient pairings, listed below.

How to use them

  1. Choose one product that contains both, or alternate days.
  2. Start 2-3 times a week.
  3. Wear sunscreen every day; AHAs increase UV sensitivity.

Every active pairing checked

ActivesVerdictWhy
Salicylic Acid + mandelic acidYes, with careYes, with care. Salicylic acid and mandelic acid can be used in one routine, but avoid stacking them daily.
Salicylic Acid + hyaluronic acidYesYes. Hyaluronic acid is a good partner for salicylic acid.

What's in each product

Key actives

Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant

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Key actives

The Ordinary Mandelic Acid 10% + HA

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Actives read from each brand's published ingredient list (as transcribed on INCIDecoder and INCIDecoder). Formulas change; check your bottle.

Sources

  1. Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. Dermatol Surg. 2009;35(1):59-65.
  2. Kornhauser A, Coelho SG, Hearing VJ. Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clin Cosmet Investig Dermatol. 2010;3:135-142.
  3. Reynolds RV, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2024;90(5):1006.e1-1006.e30.
  4. Code of Federal Regulations. 21 CFR 333.310, Acne active ingredients.
  5. U.S. Food and Drug Administration. Beta Hydroxy Acids. Cosmetic ingredients. Content current as of 02/25/2022.
  6. Dayal S, Kalra KD, Sahu P. Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris. J Cosmet Dermatol. 2020;19(2):393-399.
  7. Malviya A, Shrivastava S, Pancholi S, et al. A Prospective Study Comparing Clinical Efficacy of 30% Mandelic Acid Peel Versus 30% Lactic Acid Peel in Periorbital Melanosis. Indian Dermatol Online J. 2025;16(6):916-920.
  8. U.S. Food and Drug Administration. Alpha Hydroxy Acids. Cosmetic ingredients. Content current as of 11/22/2022.
  9. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: a key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258.
  10. Pavicic T, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990-1000.
  11. Zanchetta C, Scandolera A, Reynaud R. Hyaluronic Acid in Topical Applications: The Various Forms and Biological Effects of a Hero Molecule in the Cosmetics Industry. Biomolecules. 2025;15(12):1656.
  12. U.S. Food and Drug Administration. Dermal Fillers (Soft Tissue Fillers). Content current as of 07/06/2023.
  13. INCIDecoder. Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant: ingredient list.
  14. INCIDecoder. The Ordinary Mandelic Acid 10% + HA: ingredient list.
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