What can you mix with Tretinoin?

Prescription retinoic acid (Retin-A and others), used for acne and photoaging. The strongest common topical retinoid; dryness and irritation are common early on.

Sources

  1. Zaenglein AL, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016;74(5):945-973.
  2. Martin B, et al. Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. Br J Dermatol. 1998;139 Suppl 52:8-11.

Last reviewed: 2026-10-21. Not medical advice.